The Urbason is indicated for severe or moderately severe cases of allergy or inflammation.
Urbason is a medicine indicated in the case of inflammatory and allergic pathologies . It is a drug with a derivative of cortisone, and then we will know what cases it is used for, its recommended dose, its side effects and other relevant information.
What is Urbanason?
Urbason is a drug with an active substance called methylprednisolone . This substance is a derivative of cortisone, sharing the great anti-inflammatory activity. It has the advantage that it does not significantly alter the metabolism of glucose or proteins, nor the electrolyte balance.
It is classified within the glucocorticoids, a type of substance that has a very significant action on the body. Basically they reduce the activity of the immune system, reducing the presence of our body’s own substances that are part of inflammatory reactions.
What is it for?
This is a medication indicated for cases in which anti-inflammatory or allergic reactions are severe . This drug is used in cases where other treatments have not shown sufficient effectiveness.
Urbason is also used for people who immediately need corticosteroids in their body and there is no time or opportunity to take pills. The possibility of intravenous administration makes it a reference medicine for those acute cases of asthma that can lead to anaphylactic shocks.
Urbasol is effective in diseases such as multiple sclerosis, that is, chronic diseases of an autoimmune nature. It is also indicated in case of spinal cord injuries, trauma, metabolic disorders and cerebral edema.
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Mechanism of action
The mechanism of action of methylprednisolone is hormonal in nature , as is the case with cortisone. This substance is used to interrupt inflammatory or allergic processes thanks to its potency since it is a corticosteroid that does not have a long life.
When this substance comes into contact with the cell membrane, it is capable of interacting at different levels. Basically what it achieves is that the cell does not generate more inflammatory proteins, a natural response of the body to stress situations in which it needs to respond.
Unfortunately, the impact at the metabolic level has different unwanted effects. Glucose, proteins or vitamin D are substances that alter their normal metabolism.
presentation
Urbason is the best known brand name for methylprednisolone drugs , but there are others such as Adventan, Lexxema, Methylprednisolone Normon, or Solu-Moderin.
The presentations are variable, being able to obtain the medicine in the form of a cream, cutaneous emulsion, ointment, pills or powder for injectable solution. Thus, the mode of administration can be by topical, intramuscular, intravenous or oral route.
The intramuscular form of administration is the most widely used. The medicine comes as a powder (active ingredient) and a solvent that must be mixed together. Once the injectable solution is available, it is administered by injecting it into a well-irrigated muscle area.
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Recommended dose
The most common is the injectable Urbason in methylprednisolone concentrations of 8 mg, 20 mg, 40 mg or 250 mg . Only the fourth option has sodium in its composition and must be purchased with a prescription.
A single dose can be administered in those cases in which the person’s life is in danger. In these situations, the single dose is 250 to 1000 mg in adults, while it is 4 to 20 mg for each kilogram of weight in children.
In less severe cases the standard administration is every half hour for a day. In these cases it is 20 to 40 mg per day in adults and 8 to 16 mg in children, but the doses always depend on the opinion of medical specialists.
Side effects
Urbason is a drug considered to be highly potent and with some side effects . It is very useful in cases where the person’s life is in danger despite these side effects.
The alterations that hormonal treatments can generate occur at different levels, such as in the regulation of hunger and body weight. The concentrations in the blood of cholesterol or triglycerides is also another concern, and it is that the metabolism is affected in different parts.
This medicine inhibits the response of the immune system, so the appearance of some infections and diseases is difficult to avoid. Here is a list of different side effects that the person taking Urbason may also experience:
- skin changes
- healing problems
- growth disturbances
- Ulcers
- Alterations in fat storage
- Muscular weakness
- sweating
- dizziness
- Fatigue
- Fluid retention
- hair growth
- Erectile dysfunction
- Irregularity in the menstrual cycle
- seizures
- arrhythmias
- Thrombosis
- Glaucoma
- Osteoporosis
In addition to the side effects on a physical level, the truth is that the state of mind can be altered when taking Urbasol. Depression, mania, psychosis or confusional states may occur.
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Contraindications
There are a number of people who cannot take Urbason . These are people who, due to certain pathologies, can see their lives compromised if they take this medicine. These people are those who have any of the following conditions:
- Allergy to this medicine
- Diabetes
- Glaucoma
- Herpes
- liver problem
- heart disease
- Ulcers
- infections
- Pregnancy
- Lactation
- Urgency to receive surgery (any cause)
- mood disorders
- Psychosis
On the other hand, there are many medicines that can interact with Urbasol. It is pertinent that the doctor be consulted about the possibility of taking this drug, informing at all times of the medication that is already being taken.
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Bibliographic references
- Hamilton, R. (2015). Tarascon Pocket Pharmacopoeia 2015 Classic Shirt-Pocket Edition. Jones & Bartlett Learning.
- Lopez, C., Martinez, JM, Donado, M. (2006). Use of methylprednisolone versus diclofenac in the control of inflammation and trismus after lower third molar surgery. Med. oral pathol. oral cir.bucal, 11(5), 440-445 .
- Serra, H. A., Roganovich, J. M., & Rizzo, L.F.L. (2012). Glucocorticoids: paradigm of translational medicine. From molecular to clinical use. Medicine, 72(2), 158-170 .
To the classic question “what do you do?” I always answer “basically I am a psychologist”. In fact, my academic training has revolved around the psychology of development, education and community, a field of study influenced my volunteer activities, as well as my first work experiences in personal services.